HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-3-methoxy-5-nitrobenzaldehyde → HCID 136102564, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde | HCID 307886 | — |
| Reactant | 6-piperazin-1-yl-3H-pyrimidin-4-one | HCID 136102540 | — |
| Product | HCID 136102564 | HCID 136102564 | — |
Reaction Steps
6-[4-(2-Hydroxy-3-methoxy-5-nitro-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 3-methoxy-5-nitrosalicylaldehyde (available from Aldrich). 1H NMR (400 MHz, CDCl3) δ 2.65-2.70 (m, 4H), 3.59-3.66 (m, 4H), 3.85 (s, 2H), 3.99 (s, 3H), 5.40 (s, 1H), 7.67 (s, 1H), 7.72 (s, 1H), 7.85 (s, 1H), 12.20 (br s, 1H). Mass spectrum (ES) MH+=362.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652013B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-75fa6517586a46bc816a764b45ae74c6 |
| Source note | uspto-grants-2010_01 |