HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68539943, compound → 5-(4-Aminophenoxy)-2(1H)-pyridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68539943 | HCID 68539943 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | 1,3-Dimethyl-2-imidazolidinone | HCID 6661 | — |
| Product | 5-(4-Aminophenoxy)-2(1H)-pyridinone | HCID 58659397 | — |
Reaction Steps
Hydrogenation of 3-(4-nitro-phenoxy)-1H-pyridin-6-one (Stage 93.2; 464 mg, 2.0 mmol) in DMEU (10 ml) in the presence of Raney Nickel (100 mg) affords after filtration and concentration of the filtrate the title compound: 1H-NMR (DMSO-d6): 11.2 (s, HN), 7.25 (dd, 1H), 7.11 (d, 1H), 6.68 (d, 2H), 6.51 (d, 2H), 6.35 (d, 1H), 4.87 (s, H2N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652022B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-21312ad372b94e21b401817ca6abdefe |
| Source note | uspto-grants-2010_01 |