3-(Trifluoromethyl)phenyl isocyanate → HCID 58659415, compound

Participants

Reaction Steps

The title compound is prepared as described in Example 102 but using [6-(4-amino-benzyl)-pyrimidin-4-yl]-methyl-amine (Example 119) and α,α,α-trifluoro-m-tolyl-isocyanate. The reaction mixture is stirred for 3 h. The title compound is obtained as a white solid: ES-MS: 402.0 [M+H]+; single peak at tR=7.34 min (System 2); Rf=0.32 (CH2Cl2/MeOH, 90/10).

Provenance & Evidence