2,3,4-Tri-o-acetyl-5-thioxylopyranosyl bromide → HCID 68540786, compound

HRID 1993723Notes

Reaction equation

HRID 1993723 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[CH2:8][S:7][CH:6]1Br)(=[O:3])[CH3:2].[OH:20][C:21]1[C:26]2[N:27]=[CH:28][O:29][C:25]=2[CH:24]=[CH:23][CH:22]=1>>[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[CH2:8][S:7][C@H:6]1[O:20][C:21]1[C:26]2[N:27]=[CH:28][O:29][C:25]=2[CH:24]=[CH:23][CH:22]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 113826832,3,4-Tri-o-acetyl-5-thioxylopyranosyl bromideHCID 137206971,3-Benzoxazol-4-ol

Product 1

HCID 68540786HCID 68540786, compoundYield 41%

Procedure

By carrying out the process in a manner similar to example 7, starting from 2,3,4-tri-O-acetyl-5-thio-D-xylopyranosyl bromide and 4-hydroxybenzoxazole, the desired product is obtained in the form of a white solid with a yield of 41%.

Sources & evidence

ORD record
ord-4681db78a1004ec9bd0b17b8cd9fe06e
Source dataset
uspto-grants-2010_01
Patent number
US07652032B2

Reaction notes

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