(5-Hydroxy-1-benzofuran-3-yl)(phenyl)methanone → HCID 68541694, compound

HRID 1993725Notes

Reaction equation

HRID 1993725 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[CH2:8][S:7][CH:6]1Br)(=[O:3])[CH3:2].[C:20]([C:28]1[C:32]2[CH:33]=[C:34]([OH:37])[CH:35]=[CH:36][C:31]=2[O:30][CH:29]=1)(=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[CH2:8][S:7][C@H:6]1[O:37][C:34]1[CH:35]=[CH:36][C:31]2[O:30][CH:29]=[C:28]([C:20](=[O:27])[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:32]=2[CH:33]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 595415(5-Hydroxy-1-benzofuran-3-yl)(phenyl)methanoneHCID 113826832,3,4-Tri-o-acetyl-5-thioxylopyranosyl bromide

Product 1

HCID 68541694HCID 68541694, compoundYield 20%

Procedure

By carrying out the process in a manner similar to example 7, starting from 2,3,4-tri-O-acetyl-5-thio-D-xylopyranosyl bromide and 3-benzoyl-5-hydroxybenzofuran, the desired product is obtained in the form of a white solid with a yield of 20%.

Sources & evidence

ORD record
ord-5c62597fd2fb4121afcbe0e18184de26
Source dataset
uspto-grants-2010_01
Patent number
US07652032B2

Reaction notes

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