HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole-2-carbonitrile → HCID 11575919, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole-2-carbonitrile | HCID 138277 | — |
| Reactant | HCID 59134921 | HCID 59134921 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Product | HCID 11575919 | HCID 11575919 | — |
Reaction Steps
Copper(I) iodide catalyzed Buchwald reaction of compound 18a with 2-cyanopyrrole, following the procedure of Example 10, Step 10B, afforded 1-{3-Methoxy-4-[7-(1-methoxymethyl-propoxy)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-3-yl]-phenyl}-1H-pyrrole-2-carbonitrile (compound 18-1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652035B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-3ecaf51ecf8a4cf3a14a008a2e9394cd |
| Source note | uspto-grants-2010_01 |