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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1993880Generated: October 30, 2026

HCID 66877304, compound → trans-(5-Chloro-indan-2-ylmethyl)-[3-(2,5-dimethyl-benzoimidazol-1-yl)-cyclopentyl]-amine

https://huagongshe.com/reaction/1993880

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66877304HCID 66877304—
ReactantHCID 86620957HCID 86620957—
Producttrans-(5-Chloro-indan-2-ylmethyl)-[3-(2,5-dimethyl-benzoimidazol-1-yl)-cyclopentyl]-amineHCID 66876580—

Reaction Steps

This compound was prepared from trans-3-(2,5-dimethyl-benzoimidazol-1-yl)-cyclopentylamine hydrochloride and 5-chloro-indan-2-carbaldehyde using the same reductive amination method described in previous example. 1H-NMR is consistent with the assigned structure. LC-MS showed a single peak, C24H28ClN3 (m/e) calcd 393.1972, obsd 394.2 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07652053B2
Source datasetuspto-grants-2010_01
ORD IDord-b27444cb89124cfe91189d1c7561baeb
Source noteuspto-grants-2010_01