HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-3-(2,5-Dimethyl-benzoimidazol-1-yl)-cyclopentylamine hydrochloride → cis-(S)-(5-Bromo-indan-2-ylmethyl)-[3-(2,5-dimethyl-benzoimidazol-1-yl)-cyclopentyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-3-(2,5-Dimethyl-benzoimidazol-1-yl)-cyclopentylamine hydrochloride | HCID 66877495 | — |
| Reactant | (S)-5-bromo-indan-2-carbaldehyde | HCID 86620958 | — |
| Product | cis-(S)-(5-Bromo-indan-2-ylmethyl)-[3-(2,5-dimethyl-benzoimidazol-1-yl)-cyclopentyl]-amine | HCID 59135487 | — |
Reaction Steps
This compound was prepared from cis-3-(2,5-dimethyl-benzoimidazol-1-yl)-cyclopentylamine hydrochloride and (S)-5-bromo-indan-2-carbaldehyde using the same reductive amination method described in previous example. 1H-NMR is consistent with the assigned structure. LC-MS showed a single peak, C24H28BrN3 (m/e) calcd 437.1467, obsd 438.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652053B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-c3910a3dae0f40e09961431baa424d32 |
| Source note | uspto-grants-2010_01 |