HCID 86620957, compound → HCID 178458920, compound

HRID 1993885Notes

Reaction equation

HRID 1993885 reaction equation
[NH2:1][C@@H:2]1[CH2:7][CH2:6][C@H:5]([N:8]2[C:12]3[CH:13]=[CH:14][C:15]([Cl:17])=[CH:16][C:11]=3[N:10]=[C:9]2[C:18]([OH:21])([CH3:20])[CH3:19])[CH2:4][CH2:3]1.[Cl:22][C:23]1[CH:24]=[C:25]2[C:29](=[CH:30][CH:31]=1)[CH2:28][CH:27]([CH:32]=O)[CH2:26]2>>[Cl:17][C:15]1[CH:14]=[CH:13][C:12]2[N:8]([C@H:5]3[CH2:4][CH2:3][C@@H:2]([NH:1][CH2:32][CH:27]4[CH2:26][C:25]5[C:29](=[CH:30][CH:31]=[C:23]([Cl:22])[CH:24]=5)[CH2:28]4)[CH2:7][CH2:6]3)[C:9]([C:18]([OH:21])([CH3:19])[CH3:20])=[N:10][C:11]=2[CH:16]=1

Participants

3

Reactant 2

HCID 86620957HCID 86620957, compoundHCID 178458917HCID 178458917, compound

Product 1

HCID 178458920HCID 178458920, compound

Procedure

This compound was prepared from the hydrochloride salt of cis-2-[1-(4-amino-cyclohexyl)-5-chloro-1H-benzoimidazol-2-yl]-propan-2-ol and 5-chloro-indan-2-carbaldehyde. 1H-NMR is consistent with the assigned structure, LC-MS showed a single peak, C26H31Cl2N3O (m/e) calcd 471.1844, obsd 472.1 (M+H).

Sources & evidence

ORD record
ord-532e42efffc74a6495bebf8fb8653cb0
Source dataset
uspto-grants-2010_01
Patent number
US07652053B2

Reaction notes

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