2,3-Dihydro-1H-indene-2-carbaldehyde → HCID 178422559, compound

HRID 1993888Notes

Reaction equation

HRID 1993888 reaction equation
[CH3:1][C:2]1[N:6]([C@@H:7]2[CH2:12][CH2:11][C@H:10]([NH2:13])[CH2:9][CH2:8]2)[C:5]2[CH:14]=[CH:15][C:16]([CH3:18])=[CH:17][C:4]=2[N:3]=1.[CH2:19]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH2:21][CH:20]1[CH:28]=O>>[CH3:1][C:2]1[N:6]([C@@H:7]2[CH2:8][CH2:9][C@H:10]([NH:13][CH2:28][CH:20]3[CH2:19][C:27]4[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=4)[CH2:21]3)[CH2:11][CH2:12]2)[C:5]2[CH:14]=[CH:15][C:16]([CH3:18])=[CH:17][C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 117447712,3-Dihydro-1H-indene-2-carbaldehydeHCID 178422558HCID 178422558, compound

Product 1

HCID 178422559HCID 178422559, compound

Procedure

This compound was prepared from the hydrochloride salt of cis-4-(2,5-dimethyl-benzoimidazol-1-yl)-cyclohexylamine and indan-2-carbaldehyde. 1H-NMR is consistent with the assigned structure, LC-MS showed a single peak, C25H31N3 (m/e) calcd 373.2518, obsd 374.2 (M+H).

Sources & evidence

ORD record
ord-cf9500cf086a4671835754437c108118
Source dataset
uspto-grants-2010_01
Patent number
US07652053B2

Reaction notes

Loading…