HCID 86620957, compound → HCID 178432203, compound

HRID 1993898Notes

Reaction equation

HRID 1993898 reaction equation
[NH2:1][C@@H:2]1[CH2:7][CH2:6][C@H:5]([N:8]2[C:12]3[CH:13]=[CH:14][C:15]([C:17]#[N:18])=[CH:16][C:11]=3[N:10]=[C:9]2[CH3:19])[CH2:4][CH2:3]1.[Cl:20][C:21]1[CH:22]=[C:23]2[C:27](=[CH:28][CH:29]=1)[CH2:26][CH:25]([CH:30]=O)[CH2:24]2>>[Cl:20][C:21]1[CH:22]=[C:23]2[C:27](=[CH:28][CH:29]=1)[CH2:26][CH:25]([CH2:30][NH:1][C@@H:2]1[CH2:3][CH2:4][C@H:5]([N:8]3[C:12]4[CH:13]=[CH:14][C:15]([C:17]#[N:18])=[CH:16][C:11]=4[N:10]=[C:9]3[CH3:19])[CH2:6][CH2:7]1)[CH2:24]2

Participants

3

Reactant 2

HCID 86620957HCID 86620957, compoundHCID 178432202HCID 178432202, compound

Product 1

HCID 178432203HCID 178432203, compound

Procedure

This compound was prepared from the hydrochloride salt of cis-1-(4-amino-cyclohexyl)-2-methyl-1H-benzoimidazole-5-carbonitrile and 5-chloro-indan-2-carbaldehyde. 1H-NMR is consistent with the assigned structure, LC-MS showed a single peak, C25H27ClN4 (m/e) calcd 418.1924, obsd 419.2 (M+H).

Sources & evidence

ORD record
ord-6ca0a9d4fbac4a5b9745eec9a1223d0f
Source dataset
uspto-grants-2010_01
Patent number
US07652053B2

Reaction notes

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