Ethyl chloroformate → HCID 16037550, compound

HRID 1993953Notes

Reaction equation

HRID 1993953 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.Cl[C:17]([O:19][CH2:20][CH3:21])=[O:18]>>[CH2:20]([O:19][C:17](=[O:18])[NH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1)[CH3:21]

Participants

3

Reactant 2

HCID 10928Ethyl chloroformateHCID 160504305-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 16037550HCID 16037550, compound

Procedure

The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using ethyl chloroformate (53 μL, 0.55 mmol) to provide ethyl[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]carbamate (0.026 g).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-a321921da5064b5aa0e76ad6dd7fe593
Source dataset
uspto-grants-2010_01
Patent number
US07652062B2

Reaction notes

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