4-Chloro-3-(trifluoromethyl)aniline → HCID 58674517, compound

HRID 1994130Notes

Reaction equation

HRID 1994130 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][C:12]([OH:14])=O)=[CH:5][CH:4]=1.[Cl:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][C:17]=1[C:23]([F:26])([F:25])[F:24]>>[Cl:15][C:16]1[CH:22]=[CH:21][C:19]([NH:20][C:12](=[O:14])[CH2:11][CH2:10][CH2:9][C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)=[CH:18][C:17]=1[C:23]([F:24])([F:25])[F:26]

Participants

3

Reactant 2

HCID 675744-Chloro-3-(trifluoromethyl)anilineHCID 782804-(4-Methoxyphenyl)butyric acid

Product 1

HCID 58674517HCID 58674517, compound

Procedure

N-[4-chloro-3-(trifluoromethyl)phenyl]-4-(4-methoxyphenyl)butanamide was prepared as described in Example 5, Step 1 using 4-(4-methoxyphenyl)butyric acid and 4-chloro-3-(trifluoromethyl)aniline. LCMS, AA: Rt=2.17 min, [MH− 370.1].

Sources & evidence

ORD record
ord-048d6072a49b4e58957e8ea05a43d857
Source dataset
uspto-grants-2010_01
Patent number
US07652041B2

Reaction notes

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