HCID 58730939, compound → HCID 58730947, compound

Participants

Reaction Steps

To a stirred solution of the azaindoline 21 (20 mg, 0.10 mmol) in CH2Cl2 (2 mL) was added oven activated MnO2 (9 mg, 0.10 mmol) in one portion. After 18 h the mixture was filtered through a silica pad. The pad was washed with AcOEt and the combined organic solutions evaporated to afford the azaindole 22 (17 mg, 86%). 1H NMR (400 MHz; CDCl3) δ 0.35 (s, 9H), 6.50 (d, J=3.5 Hz, 1H), 7.35 (d, J=3.5 Hz, 1H), 8.10 (d, J=1.5 Hz, 1H), 8.40 (d, J=1.5 Hz, 1H), 10.62 (br s, NH).

Provenance & Evidence