Tropenol → HCID 86761048, compound

HRID 1994225Notes

Reaction equation

HRID 1994225 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:5]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[C:13]([CH3:19])[CH:12]=1)([OH:10])[C:6]([O:8][CH3:9])=[O:7].[C@@:25]12(O)[N:32](C)[C@@H:29]([CH2:30][CH2:31]1)[CH2:28][CH:27]=[CH:26]2>>[CH3:19][C:13]1[CH:12]=[C:11]([CH:16]=[CH:15][C:14]=1[O:17][CH3:18])[C:5]([C:4]1[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:2]([CH3:1])[CH:3]=1)([OH:10])[C:6]([O:8][C@@:9]12[N:32]([CH3:25])[C@@H:29]([CH2:30][CH2:31]1)[CH2:28][CH:27]=[CH:26]2)=[O:7]

Participants

3

Reactant 2

HCID 53629842TropenolHCID 86761049HCID 86761049, compound

Product 1

HCID 86761048HCID 86761048, compound

Procedure

4.17 is prepared analogously to the method according to II.1; the product is purified by recrystallizing from diethylether. Yield: 2.30 g (35% of theory) starting from 5.0 g (0.015 mol) of 3h and 4.21 g (0.03 mol) of tropenol; melting point: 126° C.

Workup

  1. custom4.17 is prepared analogously to the method
  2. customthe product is purified
  3. customby recrystallizing from diethylether

Sources & evidence

ORD record
ord-0d2d549a0cff4cdc97b0c8517cc54156
Source dataset
uspto-grants-2010_01
Patent number
US07652138B2

Reaction notes

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