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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1994419Generated: October 26, 2026

Quinoline-3-carboxylic acid → N-[6-(4-Chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropyl-4,7-dioxooctahydropyrazino[1,2-a]pyrimidin-3-yl]quinoline-3-carboxamide

https://huagongshe.com/reaction/1994419

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinoline-3-carboxylic acidHCID 80971—
Reactant3-Amino-6-(4-chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropylhexahydropyrazino[1,2-a]pyrimidine-4,7-dioneHCID 59134252—
ProductN-[6-(4-Chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropyl-4,7-dioxooctahydropyrazino[1,2-a]pyrimidin-3-yl]quinoline-3-carboxamideHCID 59134221—

Reaction Steps

Synthesis took place in analogy to Example 29e using 3-quinolinecarboxylic acid and 3-amino-6-(4-chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropyl-hexahydropyrazino[1,2-a]pyrimidine-4,7-dione. The desired product is obtained with MW=713.10 (calculated, monoisotopic); measured value (M+H)+:714

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07652007B2
Source datasetuspto-grants-2010_01
ORD IDord-50b58894a3de4dfc8465b6cd9895a5ed
Source noteuspto-grants-2010_01