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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 199475Generated: October 25, 2026

Dichloromethane → tert-Butyl 1-(4-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-2-methoxyphenoxy)-2-methylpropan-2-yl Malonate

https://huagongshe.com/reaction/199475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylcarbodiimideHCID 12734—
Reactant3-(Tert-butoxy)-3-oxopropanoic acidHCID 545853—
Reactant6-(4-chlorophenyl)-3-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-oneHCID 16718619—
Producttert-Butyl 1-(4-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-2-methoxyphenoxy)-2-methylpropan-2-yl MalonateHCID 58858121—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-cc00bd3742af4a2d9dfc215b8d71d5e9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)