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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 199478Generated: October 29, 2026

Hydrochloric Acid → 2-(2-Chloro-5-fluoropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid

https://huagongshe.com/reaction/199478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
ReactantPalladium ChlorideHCID 24290—
Reactant2,4-Dichloro-5-fluoropyrimidineHCID 250705—
Reactant(4-Carboxybenzo[b]thiophen-2-yl)boronic acidHCID 67272237—
Product2-(2-Chloro-5-fluoropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acidHCID 86625344—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-5e9adc0a2d03400c818a6c55328f6b62
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)