反应详情

A solution of 0.5 g. (0.0027 mole) of 2-hydrazino-5-phenylpyrazine in 5.0 ml. of triethyl orthoacetate is heated under reflux for 5 hours. The crystalline product precipitates from the hot reaction solution, and at the end of the heating period the mixture is cooled and the product is collected. Recrystallization from ethanol gives 0.36 g. of the product of the example, m.p. 192°-195° C.

1. temperatureunder reflux for 5 hours
2. customThe crystalline product precipitates from the hot reaction solution
3. temperatureat the end of the heating period the mixture is cooled
4. customthe product is collected
5. customRecrystallization from ethanol
6. customgives 0.36 g