Carbon Dioxide → HCID 12853038, compound

HRID 1995109Notes

Reaction equation

HRID 1995109 reaction equation
C([C:4]([C:22](=O)[CH3:23])([CH:10]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[F:21])[CH2:11][C:12]([O-:14])=O)[C:5]([O:7][CH2:8][CH3:9])=[O:6])(=O)C.[C:25](=O)=O>C(O)C>[F:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[CH:10]1[CH2:11][C:12](=[O:14])[CH:25]=[C:22]([CH3:23])[CH:4]1[C:5]([O:7][CH2:8][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 280Carbon DioxideHCID 20270645HCID 20270645, compound

Product 1

HCID 12853038HCID 12853038, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The ethyl α,α-diacetyl-β-(2-fluorophenyl)glutarate was heated under vacuum at 160°-180°/10-15 mm for 1 hr, eliminating carbon dioxide and ethanol and producing 5-(2-fluorophenyl)-3-methyl-4-carbethoxy-2-cyclohexen-1-one. The crude product was distilled under reduced pressure to give 5-(2-fluorophenyl)-3-methyl-4-carbethoxy-2-cyclohexen-1-one (57.3 g); bp, 155°-162°/1.2 mm.

Sources & evidence

ORD record
ord-5fdf7fcf0ede4ee282c7f1815503049f
Source dataset
uspto-grants-1983_09
Patent number
US04402973

Reaction notes

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