HCID 86739003, compound → HCID 12807753, compound

Participants

Reaction Steps

A mixture of 2.3 g of the product of Step C, 20 mg of hydrated p-toluene sulfonic acid and 20 ml of toluene was refluxed for 40 minutes and the mixture was then evaporated to dryness under reduced pressure. The 2.1 g of residue were chromatographed over silica gel and were eluted with a 60-39-1 cyclohexane-ethyl acetate-acetic acid mixture to obtain 1.5 g of (1R,cis) 2,2-dimethyl-3-[Z-2-(ethoxycarbonyl)-ethenyl]-cyclopropane-carboxylic acid melting at 96° C.

Provenance & Evidence