Dimethylamine → HCID 15583152, compound

HRID 1995248Notes

Reaction equation

HRID 1995248 reaction equation
[CH3:1][NH:2][CH3:3].[CH3:4][N:5]([N:16]1[C:24](=[O:25])[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:17]1=[O:26])[C:6](=[N:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)SC>C(O)C>[CH3:1][N:2]([CH3:3])[C:6]([N:5]([CH3:4])[N:16]1[C:24](=[O:25])[C:23]2=[CH:22][CH:21]=[CH:20][CH:19]=[C:18]2[C:17]1=[O:26])=[N:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 674DimethylamineHCID 12768103HCID 12768103, compound

Product 1

HCID 15583152HCID 15583152, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a saturated solution of anhydrous dimethylamine in 80 ml. of ethanol was added 4.53 g. (0.01 mol) of 2-(1,2-dimethyl-3-phenylisothioureido)-1H-isoindole-1,3-(2H)-dione, and the resulting solution was heated to 50° C. for 30 minutes. Evaporation and treatment with heptane gave 3.5 g. of crystalline product, m.p. 146°-8° C.

Workup

  1. customEvaporation and treatment with heptane
  2. customgave 3.5 g

Sources & evidence

ORD record
ord-8f0abf372de341dab318de15d8e2d2d8
Source dataset
uspto-grants-1983_09
Patent number
US04404017

Reaction notes

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