HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13189010, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-(2-Chloroethyl)-3-azabicyclo[3.2.2]nonane--hydrogen chloride (1/1) | HCID 12612326 | — |
| Reactant | 8-Methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one | HCID 13136918 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13189010 | HCID 13189010 | 51.4% |
Reaction Steps
A mixture of 8-methoxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-one (2.31 g, 0.01 mole), 3-(2-chloroethyl)-3-azabicyclo(3.2.2)nonane hydrochloride (2.49 g, 0.01 mole) and triethylamine (3.03 g) in absolute ethanol (50 ml) is refluxed for 24 hours. The reaction mixture is filtered. Hydrogen chloride gas is bubbled through the filtrate. The product is filtered off, washed with ethanol and sucked dry. Recrystallization from methanol gave the product (2.34 g), mp 265°-270° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404138 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-214677168f554228a8edc1147628bd49 |
| Source note | uspto-grants-1983_09 |