HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13189026, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 8,9-dimethoxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-c]pyridin-5-one | HCID 10825289 | — |
| Reactant | 3-(2-Chloroethyl)-3-azabicyclo[3.2.2]nonane--hydrogen chloride (1/1) | HCID 12612326 | — |
| Product | HCID 13189026 | HCID 13189026 | 34% |
Reaction Steps
Prepared by the method described in Example 9 from 1,2,3,4-tetrahydro-8,9-dimethoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one (5.2 g, 0.020 moles), triethylamine (4.9 g, 0.048 moles), and 3-(2-chloroethyl)-3-azabicyclo[3.2.2]nonane hydrochloride (5.4 g, 0.024 moles). Recrystallization from methanol yielded the final product (3.3 g) as the dihydrochloride, mp 229°-234° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404138 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-27c11fe6a39a4da6a9e5bf254850b670 |
| Source note | uspto-grants-1983_09 |