HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13189036, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 8,9-dimethoxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-c]pyridin-5-one | HCID 10825289 | — |
| Reactant | 3-(2-Chloroethyl)-3-azabicyclo[3.3.1]nonane hydrochloride | HCID 20488143 | — |
| Product | HCID 13189036 | HCID 13189036 | 63.9% |
Reaction Steps
Prepared by the method described for Example 13 from 1,2,3,4-tetrahydro-8,9-dimethoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one (3.0 g, 0.011 moles), triethylamine (6.4 ml, 0.046 moles), and 3-(2-chloroethyl)-3-azabicyclo[3.3.1]nonane hydrochloride (3.0 g, 0.013 moles). The reflux time is 96 hours. Recrystallization from ethanol gave the product (2.9 g), mp 122°-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404138 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-52509b50f8e44333a7d8073b7d2cb1f4 |
| Source note | uspto-grants-1983_09 |