3-(Acetylthio)-2-methylpropanoic acid → HCID 13069272, compound

HRID 1995328Notes

Reaction equation

HRID 1995328 reaction equation
C([S:4][CH2:5][CH:6]([CH3:10])[C:7]([OH:9])=O)(=O)C.[C:11]([CH:16]1[CH2:24][CH:23]2[CH:18]([CH2:19][CH2:20][CH2:21][CH2:22]2)[NH:17]1)([O:13]CC)=[O:12].C(C1CC2C(=CC=CC=2)N1)(OCC)=O>>[SH:4][CH2:5][CH:6]([CH3:10])[C:7]([N:17]1[CH:18]2[CH:23]([CH2:22][CH2:21][CH2:20][CH2:19]2)[CH2:24][CH:16]1[C:11]([OH:13])=[O:12])=[O:9]

Participants

4

Reactant 3

HCID 1180733-(Acetylthio)-2-methylpropanoic acidHCID 11949691Ethyl Indoline-2-carboxylateHCID 13069248Ethyl octahydro-1H-indole-2-carboxylate

Product 1

HCID 13069272HCID 13069272, compound

Procedure

Using the method described in example 1, beginning with 3-acetylthio 2-(RS) methylpropionic acid and 2-(RS) carbethoxy perhydroindole, prepared by reduction of 2(RS) carbethoxy indoline according to the method described in example 13, the following are obtained successively:

Workup

  1. customthe following are obtained successively

Sources & evidence

ORD record
ord-7c2843dcfefc450288da42f1e91fc300
Source dataset
uspto-grants-1983_09
Patent number
US04404206

Reaction notes

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