Sulfuric Acid → HCID 10656308, compound

HRID 1995347Notes

Reaction equation

HRID 1995347 reaction equation
[O:1]=[C:2]1[CH:7]=[C:6]([C:8]#[N:9])[C:5]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[N:4][NH:3]1.S(=O)(=O)(O)[OH:17]>>[O:1]=[C:2]1[CH:7]=[C:6]([C:8]([NH2:9])=[O:17])[C:5]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[N:4][NH:3]1

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 10774296HCID 10774296, compound

Product 1

HCID 10656308HCID 10656308, compound

Procedure

2,3-Dihydro-3-oxo-6-phenyl-5-pyridazinecarbonitrile (10.0 g) is added to cold (0°-5° C.) concentrated sulfuric acid (50 ml) and the resulting solution is kept at 0°-5° C. for 24 hours and then poured onto crushed ice and the solid product is collected and recrystallized from aqueous ethanol to give 2,3-dihydro-3-oxo-6-phenyl-5-pyridazinecarboxamide.

Workup

  1. additionpoured
  2. customonto crushed ice
  3. customthe solid product is collected
  4. customrecrystallized from aqueous ethanol

Sources & evidence

ORD record
ord-3d5d891d18194309ac200c8399f81668
Source dataset
uspto-grants-1983_09
Patent number
US04404203

Reaction notes

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