Thionyl Chloride → HCID 178439103, compound

HRID 1995352Notes

Reaction equation

HRID 1995352 reaction equation
[CH2:1]([C:4]1[N:9]=[C:8]([C:10]([OH:12])=O)[CH:7]=[CH:6][CH:5]=1)[CH2:2][CH3:3].S(Cl)(Cl)=O.[NH2:17][C:18]1[NH:22][N:21]=[N:20][N:19]=1>>[NH:19]1[C:18]([NH:17][C:10]([C:8]2[CH:7]=[CH:6][CH:5]=[C:4]([CH2:1][CH2:2][CH3:3])[N:9]=2)=[O:12])=[N:22][N:21]=[N:20]1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 13209530HCID 13209530, compoundHCID 178509299HCID 178509299, compound

Product 1

HCID 178439103HCID 178439103, compoundYield 9.9%

Procedure

1.9 g of 6-n-propyl-2-pyridinecarboxylic acid, 12 ml of thionyl chloride and 0.96 g of 5-aminotetrazole are treated in the same manner as described in Example 1. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and water, whereby 0.26 g of N-(5-tetrazolyl)-6-n-propyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and water

Sources & evidence

ORD record
ord-40a132fadc434613a8b8b7bb34aaedbc
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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