Thionyl Chloride → HCID 178440878, compound

HRID 1995353Notes

Reaction equation

HRID 1995353 reaction equation
[CH2:1]([C:5]1[N:10]=[C:9]([C:11]([OH:13])=O)[CH:8]=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].S(Cl)(Cl)=O.[NH2:18][C:19]1[NH:23][N:22]=[N:21][N:20]=1>>[NH:20]1[C:19]([NH:18][C:11]([C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH2:1][CH2:2][CH2:3][CH3:4])[N:10]=2)=[O:13])=[N:23][N:22]=[N:21]1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 13209533HCID 13209533, compoundHCID 178509299HCID 178509299, compound

Product 1

HCID 178440878HCID 178440878, compoundYield 34.5%

Procedure

2.4 g of 6-n-butyl-2-pyridinecarboxylic acid, 15 ml of thionyl chloride and 0.97 g of 5-aminotetrazole are treated in the same manner as described in Example 1. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.97 g of N-(5-tetrazolyl)-6-n-butyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and ethanol

Sources & evidence

ORD record
ord-f88241ddd2a54055afc642ac464d9eaf
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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