4-ethylpyridine-2-carboxylic Acid → HCID 178436811, compound

HRID 1995363Notes

Reaction equation

HRID 1995363 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[C:5]([C:9]([OH:11])=O)[CH:4]=1)[CH3:2].[NH2:12][C:13]1[NH:17][N:16]=[N:15][N:14]=1>>[NH:14]1[C:13]([NH:12][C:9]([C:5]2[CH:4]=[C:3]([CH2:1][CH3:2])[CH:8]=[CH:7][N:6]=2)=[O:11])=[N:17][N:16]=[N:15]1

Participants

3

Reactant 2

HCID 35965804-ethylpyridine-2-carboxylic AcidHCID 178509299HCID 178509299, compound

Product 1

HCID 178436811HCID 178436811, compoundYield 24.1%

Procedure

0.46 g of 4-ethyl-2-pyridinecarboxylic acid, 0.5 g of N,N'-carbonyldiimidazole and 0.28 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and water, whereby 0.16 g of N-(5-tetrazolyl)-4-ethyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and water

Sources & evidence

ORD record
ord-fc5c82a9f2514ecb8b8140c362bfc259
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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