6-Phenoxypyridine-2-carboxylic acid → HCID 178522676, compound

HRID 1995373Notes

Reaction equation

HRID 1995373 reaction equation
[O:1]([C:8]1[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:17][C:18]1[NH:22][N:21]=[N:20][N:19]=1>>[NH:19]1[C:18]([NH:17][C:14]([C:12]2[CH:11]=[CH:10][CH:9]=[C:8]([O:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[N:13]=2)=[O:16])=[N:22][N:21]=[N:20]1

Participants

3

Reactant 2

HCID 132095796-Phenoxypyridine-2-carboxylic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178522676HCID 178522676, compoundYield 39.6%

Procedure

0.25 g of 6-phenoxy-2-pyridinecarboxylic acid, 0.2 g of N,N'-carbonyldiimidazole and 0.11 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from ethanol, whereby 0.13 g of N-(5-tetrazolyl)-6-phenoxy-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from ethanol

Sources & evidence

ORD record
ord-2d5c1dd8b291429487232611916bc011
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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