HCID 13209586, compound → HCID 178492287, compound

HRID 1995376Notes

Reaction equation

HRID 1995376 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([CH3:9])[N:6]=[C:5]([C:10]([OH:12])=O)[CH:4]=1.[NH2:13][C:14]1[NH:18][N:17]=[N:16][N:15]=1>>[NH:15]1[C:14]([NH:13][C:10]([C:5]2[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([CH3:9])[N:6]=2)=[O:12])=[N:18][N:17]=[N:16]1

Participants

3

Reactant 2

HCID 13209586HCID 13209586, compoundHCID 178509299HCID 178509299, compound

Product 1

HCID 178492287HCID 178492287, compoundYield 73.2%

Procedure

0.8 g of 4-methoxy-6-methyl-2-pyridinecarboxylic acid, 0.82 g of N,N'-carbonyldiimidazole and 0.45 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.82 g of N-(5-tetrazolyl)-4-methoxy-6-methyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and ethanol

Sources & evidence

ORD record
ord-db722d99b5134755b5b240a5707d3471
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

Loading…