Ethanol → HCID 20230482, compound

HRID 1995377Notes

Reaction equation

HRID 1995377 reaction equation
Cl.[OH:2][C:3]1[CH:13]=[CH:12][C:11]([CH:14]([Cl:20])[CH2:15][NH:16][CH:17]([CH3:19])[CH3:18])=[CH:10][C:4]=1[NH:5][S:6]([CH3:9])(=[O:8])=[O:7].[CH2:21]([OH:23])[CH3:22]>>[ClH:20].[OH:2][C:3]1[CH:13]=[CH:12][C:11]([CH:14]([O:23][CH2:21][CH3:22])[CH2:15][NH:16][CH:17]([CH3:19])[CH3:18])=[CH:10][C:4]=1[NH:5][S:6]([CH3:9])(=[O:8])=[O:7]

Participants

3

Reactant 2

HCID 702EthanolHCID 20230479HCID 20230479, compound

Product 1

HCID 20230482HCID 20230482, compound

Procedure

A 1 g sample of 2'-hydroxy-5'-[1-chloro-2-(isopropylamino)ethyl]methanesulfonanilide hydrochloride is added to 10 ml of absolute ethanol and heated at reflux for 30 minutes. The mixture is evaporated to dryness and the residue is washed with ethyl ether thus yielding the product compound.

Workup

  1. temperatureheated
  2. temperatureat reflux for 30 minutes
  3. customThe mixture is evaporated to dryness
  4. washthe residue is washed with ethyl ether
  5. customthus yielding the product compound

Sources & evidence

ORD record
ord-1fc1fd7e6e2a415fa1eddd20d3b23058
Source dataset
uspto-grants-1983_09
Patent number
US04404224

Reaction notes

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