HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenolate Sodium → HCID 20230481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenolate Sodium | HCID 4445035 | — |
| Reactant | HCID 20230479 | HCID 20230479 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20230481 | HCID 20230481 | — |
Reaction Steps
A 3.25 g sample of 2'-hydroxy-5'-[1-chloro-2-(isopropylamino)ethyl]methanesulfonanilide hydrochloride is slowly added to 45 g of sodium phenoxide in 150 ml of dry tetrahydrofuran at 0° to 5° C. under N2 atmosphere. The mixture is stirred for 24 hours at ambient temperature and then poured on ice whereafter the crude product compound is separated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404224 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-15253e0ab23a4cbda1514cba2841de2d |
| Source note | uspto-grants-1983_09 |