HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 2-chloro-6-nitro-, methyl ester → Methyl 2-amino-6-chlorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 2-chloro-6-nitro-, methyl ester | HCID 603613 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-amino-6-chlorobenzoate | HCID 592849 | — |
Reaction Steps
4.5 gm (0.212 mol) of methyl 6-chloro-2-nitro-benzoate were hydrogenated with Raney nickel in 1.8 liters of methanol until the calculated amount of hydrogen was absorbed. The filtered reaction mixture was evaporated in vacuo, and the residue was distilled in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404230 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-ff8c8899ad384fc487339258c97eb69f |
| Source note | uspto-grants-1983_09 |