Glyoxylic Acid → HCID 70520923, compound

HRID 1995424Notes

Reaction equation

HRID 1995424 reaction equation
[N:1]1[C:8]([NH2:9])=[N:7][C:5]([NH2:6])=[N:4][C:2]=1[NH2:3].[C:10]([OH:14])(=[O:13])[CH:11]=[O:12]>CS(C)=O>[CH3:2][O:12][CH2:11][C:10]([OH:14])=[O:13].[CH3:10][NH:3][C:2]1[N:4]=[C:5]([NH2:6])[N:7]=[C:8]([NH2:9])[N:1]=1

Participants

4

Reactant 2

HCID 760Glyoxylic AcidHCID 7955Melamine

Product 1

HCID 70520923HCID 70520923, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Melamine and glyoxylic acid are dissolved in dimethylsulfoxide and heated to 50°-80° C. for 5-8 hours. The solvent is removed and replaced by methanol. Sulfuric acid is added as a catalyst and the mixture heated to reflux for 5-10 hours, at which the solution is dried with a drying agent, i.e., 3A molecular sieve. The catalyst is neutralized with base and the methanol removed. The remaining mixture is filtered to yield methyl melamine glycolate methyl ether.

Workup

  1. temperatureheated to 50°-80° C. for 5-8 hours
  2. customThe solvent is removed
  3. additionSulfuric acid is added as a catalyst
  4. temperaturethe mixture heated
  5. temperatureto reflux for 5-10 hours, at which the solution
  6. dry with materialis dried with a drying agent, i.e., 3A molecular sieve
  7. customthe methanol removed
  8. filtrationThe remaining mixture is filtered

Sources & evidence

ORD record
ord-3494042fb61746b685f104b426834475
Source dataset
uspto-grants-1983_09
Patent number
US04404332

Reaction notes

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