HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → N-cyclohexyl-hexahydropyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | N-Cyclohexyl-1,3-propanediamine | HCID 18718 | — |
| Solvent | Cyclohexane | HCID 8078 | — |
| Product | N-cyclohexyl-hexahydropyrimidine | HCID 12676278 | 73.8% |
Reaction Steps
312 g of N-cyclohexyl-1,3-propanediamine are slowly added dropwise at 60° C. to a suspension of 66 g of paraformaldehyde in 200 ml of cyclohexane. The water of reaction is then removed by boiling under reflux on a water separator. Insoluble constituents are removed by filtration and the filtrate is subjected to fractional distillation. 248 g of N-cyclohexyl-hexahydropyrimidine boiling at from 87° to 91° C. at 0.3 mbar are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404379 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-34bc45edeb134bd79561a8997096a05d |
| Source note | uspto-grants-1983_09 |