HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrimidine, 1,4,5,6-tetrahydro-2-(methylthio)-, hydriodide (1:1) → HCID 178515260, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrimidine, 1,4,5,6-tetrahydro-2-(methylthio)-, hydriodide (1:1) | HCID 199998 | — |
| Reactant | 1H-Imidazole, 4,5-dihydro-2-(methylthio)-, hydriodide (1:1) | HCID 12221228 | — |
| Reactant | HCID 178508071 | HCID 178508071 | — |
| Product | HCID 178515260 | HCID 178515260 | — |
Reaction Steps
- Procedure 1 is repeated with substitution of 2-(methylthio)-3,4,5,6-tetrahydropyrimidine hydroiodide for the 2-(methylthio)-2-imidazoline hydroiodide specified. The resulting 8-amino-3,4-dihydro-9-[(4-chlorophenyl)methyl]-7-nitroso-2H,5H-pyrimido(1,2-a)pyrimidin-6(9H)-one is converted to the corresponding 7-formylamino compound to the method of Procedure 2, and the latter is then cyclized to the desired product by the method of Procedure 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404380 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-c93f2db931da4335b418a477a66946e3 |
| Source note | uspto-grants-1983_09 |