HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-[(2-chlorophenyl)methyl]-N-hydroxy-2,2-dimethylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | N-(2-ChlorobenZyl)hydroxylamine | HCID 12811040 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[(2-chlorophenyl)methyl]-N-hydroxy-2,2-dimethylpropanamide | HCID 13192549 | 29% |
Reaction Steps
This compound was prepared in the manner of Example 1, Step C, using 6.0 grams (0.05 mole) of trimethylacetyl chloride, 9.5 grams (0.06 mole) of N-(2-chlorophenylmethyl)hydroxylamine (prepared in Example I, Step A), and 14.2 grams (0.18 mole) of pyridine in 60 ml of methylene chloride. The crude product was recrystallized from hexane to give 3.5 grams of N-(2-chlorophenyl)methyl-N-hydroxy-2,2-dimethylpropanamide; mp 100°-102°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405357 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-729d60b841474856b5e2b8814836c3f2 |
| Source note | uspto-grants-1983_09 |