Methanol → HCID 13067125, compound

Participants

Reaction Steps

In one portion 0.2 g (5.2 mmol) of sodium borohydride was added to 0.9 g of 8-chloro-6-(2-chlorophenyl)-2H,4H-pyrrolo[3,4-d][2]benzazepine-3-carboxaldehyde in 20 ml of methanol which was cooled to 0°. After stirring at 0° for 30 min, water was added and the resulting precipitate was collected by filtration to give a tan amorphous solid (mp 170°-180° dec.). All attempts to purify this product led to the introduction of impurities by decomposition.

Provenance & Evidence