HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → N-(hydroxyethoxyethoxyethyl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-Chloroethoxyethoxyethanol | HCID 18350357 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-(hydroxyethoxyethoxyethyl)pyrrolidine | HCID 57119225 | 76% |
Reaction Steps
A total of 295 g of pyrrolidone and 250 g of 2-chloroethoxyethoxyethanol in 750 ml of ethanol was refluxed for 5 hours. The reaction mixture was then treated with 106 g of KOH and refluxed for an additional hour. Filtration and distillation yielded 229 g of N-(hydroxyethoxyethoxyethyl)pyrrolidine (b.p.=145° C. at 3 mm).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405582 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-022f33e858d94b358a17e7546382fa75 |
| Source note | uspto-grants-1983_09 |