3-Bromopropylamine hydrobromide → HCID 85445243, compound

Participants

Reaction Steps

A solution of sodium (0.09 g, 0.004 mol) in methanol (10 ml) was added dropwise to a stirred solution of 1-nitro-2-methylthio-2-methylsulphinyl-ethylene (0.5 g, 0.003 mol) and 3-bromopropylamine hydrobromide (0.9 g, 0.004 mol) in methanol (30 ml). The mixture was stirred for 5 hours, and then the solvent was removed in vacuo. The residue was dissolved in water (20 ml) and extracted with chloroform (2×30 ml). The extracts were combined, dried, and concentrated in vacuo. The solid residue was recrystallised from propan-2-ol to give 1-nitro-2-methylthio-2-(3-bromopropylamino)ethylene (0.3 g, 43%) m.p. 92°-92.5°. Found: C, 28.2; H, 4.3; N, 10.9; S, 12.5; Br, 31.3; C6H11BrN2O2S requires: C, 28.2; H, 4.35; N, 11.0; S, 12.6; Br, 31.3%.

Provenance & Evidence