HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1995659Generated: October 30, 2026
Diethyl Ether → 4-Benzoyl-5-methyl-1,3-dihydro-2H-imidazol-2-one
https://huagongshe.com/reaction/1995659
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | HCID 22290139 | HCID 22290139 | — |
| Solvent | Nitrobenzene | HCID 7416 | — |
| Product | 4-Benzoyl-5-methyl-1,3-dihydro-2H-imidazol-2-one | HCID 15567531 | — |
Reaction Steps
To a solution of 3.0 g of 4-methylimidazol-2-one and 8.0 g of aluminum chloride in 50 ml of nitrobenzene is added dropwise 4.6 g of benzoyl chloride. The solution is warmed at 60° C. for 4 hours, poured over ice water, slurried with ether and the resulting solids filtered and dried to yield the title compound. M.P. 250°-54° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04405635 |
|---|
| Source dataset | uspto-grants-1983_09 |
|---|
| ORD ID | ord-4f9d0ced93ab486c9de2575f0b115003 |
|---|
| Source note | uspto-grants-1983_09 |
|---|
