HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1995717Generated: October 31, 2026
1,1,1,2-Tetrachloroethane → HCID 70090355, compound
https://huagongshe.com/reaction/1995717
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,1,1,2-Tetrachloroethane | HCID 12418 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | Isonicotinoyl chloride hydrochloride | HCID 12262826 | — |
| Reactant | 4-ethyl-2,3-dihydro-1H-imidazol-2-one | HCID 15567528 | — |
| Product | HCID 70090355 | HCID 70090355 | — |
Reaction Steps
To 3.0 g (27 mmole) of 1,3-dihydro-4-ethyl-2H-imidazole-2-one and 4.74 g (27 mmole) isonicotinoyl chloride hydrochloride in 100 ml tetrachloroethane is added 21.3 g (160 mmole) aluminum chloride. The mixture is stirred at 85° C. for 4 hours and quenched with water. The solution is neutralized with sodium bicarbonate and the suspension filtered. The residue is washed with ethanol and the combined filtrates evaporated to dryness. Chromatography on silica gel afforded the title compound; m.p. 260°-63°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04405628 |
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| Source dataset | uspto-grants-1983_09 |
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| ORD ID | ord-d03a3e9c0f474476b40cf73296ef0c87 |
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| Source note | uspto-grants-1983_09 |
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