反应详情

温度

80 °C

Example 1 is repeated using 1.0 g of 6-carboxy-3-mercapto-4-amino-1,2,4-triazin-5-one, prepared from ketomalonic acid hydrate and thiocarbohydrazide as previously described in my application Ser. No. 6/238,480 (filed 2/26/81), in 30 ml of acetic anhydride. The reaction mixture is heated at 80° C. to dissolve the acid; then for one hour at 90° C. and then for 3 hours at 110° C. The product, isolated as before, melts at 50°-60° C. and is soluble in acetone and alcohol. It decomposes at about 120° C. Anal. Calcd. for C10H14O4N4S: S, 11.29. Found: S, 11.29.

1. dissolutionto dissolve the acid
2. waitfor 3 hours at 110° C
3. customThe product, isolated as before, melts at 50°-60° C.
4. customdecomposes at about 120° C