HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → HCID 3062248, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Indole, 5-methoxy-3-(4-piperidylmethyl)- | HCID 19027 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 3062248 | HCID 3062248 | — |
Reaction Steps
The operation is as in Example 1, but starting from 10.2 g of 4-[(5-methoxy-3-indolyl)-methyl]-piperidine and 0.21 g of triethylbenzylammonium chloride in 100 ml of chloroform, and 12.5 g of sodium hydroxide in solution in 25 ml of water. 3.7 g of 3-chloro-6-methoxy-4-[(4-piperidyl)-methyl]-quinoline are finally obtained, the monohydrochloride of which melts above 260° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405789 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-41786d18c3694d6dbb00f3bf8481cf4c |
| Source note | uspto-grants-1983_09 |