HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → HCID 3062239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 20431849 | HCID 20431849 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 3062239 | HCID 3062239 | — |
Reaction Steps
The operation is as in Example 1, but starting from 9.5 g of 4-[(7-methyl-3-indolyl)-methyl]-piperidine and 0.21 g of triethylbenzylammonium chloride in 100 ml of chloroform, and 12.5 g of sodium hydroxide in solution in 25 ml of water. 5.1 g of 3-chloro-8-methyl-4-[(4-piperidyl)-methyl]-quinoline are finally obtained, the monohydrochloride of which melts at 252° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405789 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-0bc893339eb348cb8feafc703e9c5beb |
| Source note | uspto-grants-1983_09 |