HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → HCID 3062243, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-[2-(Piperidin-3-yl)ethyl]-1H-indole | HCID 20431850 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 3062243 | HCID 3062243 | — |
Reaction Steps
The operation is as in Example 1, but starting from 3.8 g of 3-[2-(3-indolyl)-ethyl]-piperidine and 0.075 g of benzyltriethylammonium chloride in 40 ml of chloroform, and 5 g of sodium hydroxide in 10 ml of water. 1.3 g of 3-chloro-4-[2-(3-piperidyl)-ethyl]-quinoline are finally obtained in the form of the dihydrated monohydrochloride melting at 75° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405789 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-7a65d840e6884184b24f09b0ab6d196a |
| Source note | uspto-grants-1983_09 |