HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5,6-Tetrahydrophthalic anhydride → HCID 20486113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5,6-Tetrahydrophthalic anhydride | HCID 12475 | — |
| Reactant | 6-[2-(4-Chlorophenyl)ethoxy]pyridin-3-amine | HCID 20486085 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 20486113 | HCID 20486113 | — |
Reaction Steps
A mixture of 3,4,5,6-tetrahydrophthalic anhydride (0.4 g), 5-amino-2-(4-chlorophenethoxy)pyridine (0.6 g) and acetic acid (20 ml) is heated to reflux. After about 1.5 hours, the reaction is cooled and concentrated to about one-half volume. On standing a crystalline solid precipitation which is collected by filtration and washed with 10% ethyl acetate/hexane to yield N-[2-(4-chlorophenethoxy)-5-pyridyl]-3,4,5,6-tetrahydrophthalimide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04406690 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-eaf340beb03e4037bcb23aab7f07ad1c |
| Source note | uspto-grants-1983_09 |