HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 178514957, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 3,4,5,6-Tetrahydrophthalic anhydride | HCID 12475 | — |
| Reactant | 2-Amino-6-hydroxypyridine | HCID 178507634 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 178514957 | HCID 178514957 | — |
Reaction Steps
A mixture of 2-amino-6-hydroxypyridine (2.2 g), 3,4,5,6-tetrahydrophthalic anhydride (3.0 g) and acetic acid (40 ml) is heated to reflux for about 18 hours. The reaction is then cooled and stripped. The concentrate is taken up in CHCl3 (100 ml), washed with water, dried and stripped to yield N-(6-hydroxy-2-pyridyl)-3,4,5,6-tetrahydrophthalimide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04406690 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-13271fdae5f7462fb11e2a7f4398c208 |
| Source note | uspto-grants-1983_09 |